Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667763 | 0.91 | KDM4E (0.55) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL9667689 | 0.87 | ALDH1A1 (0.72) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL7809358 | 0.85 | ALDH1A1 (0.76) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL10915571 | 0.83 | KDM4E (0.62) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL9668111 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9666671 | 0.82 | KDM4E (0.52) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9666639 | 0.82 | LMNA (0.45) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL9668000 | 0.82 | LMNA (0.56) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL9218049 | 0.81 | LMNA (0.46) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL6211422 | 0.81 | ALDH1A1 (0.49) | ALDH1A1DRD3KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324298-B1 | 7-(1-AZETIDINYL)-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-12-23 | — | — | EP | claimed |