Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494111 | 0.77 | ALDH1A1 (0.38) | TSHRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL8488644 | 0.76 | ALDH1A1 (0.36) | TSHRLMNAMAPT | |
| SCHEMBL8989195 | 0.74 | HTR3E (0.41) | NOS3NOS1NOS2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL9668702 | 0.72 | HPGD (0.37) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL1154462 | 0.69 | — | — | |
| SCHEMBL27170376 | 0.65 | ALDH1A1 (0.43) | PLGTSHRMAPT | |
| SCHEMBL19242050 | 0.65 | ALDH1A1 (0.48) | PLGTSHRLMNAMAPT | |
| SCHEMBL19241690 | 0.65 | ALDH1A1 (0.43) | PLGTSHRMAPT | |
| SCHEMBL15150060 | 0.64 | PLG (0.38) | PLGTSHRLMNAMAPT | |
| SCHEMBL7089009 | 0.64 | PLG (0.38) | PLGTSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363061-B1 | IMIDAZOLINE DERIVATIVE AND PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |
| US-5051441-A | Immunomodulators and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-24 | — | — | US | disclosed |
| EP-0363061-A1 | Imidazoline derivative and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1990-04-11 | — | — | EP | disclosed |