Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668943 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9667652 | 0.87 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9667678 | 0.85 | AGTR2 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9667357 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9668613 | 0.84 | TLR7 (0.52) | TLR7AGTR1AGTR2PI4KAPI4K2B | |
| SCHEMBL9705910 | 0.82 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9704785 | 0.81 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9704895 | 0.81 | KDM4E (0.59) | AGTR1AGTR2 | |
| SCHEMBL9704742 | 0.80 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9704677 | 0.80 | AGTR1 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467207-A2 | Purinderivate | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-22 | — | — | EP | claimed |
| EP-0514515-A1 | ANTHRACYCLINE-CONJUGATES. | ERBA CARLO SPA (IT) | 1992-11-25 | — | — | EP | disclosed |