Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609023 | 0.70 | DDB1 (0.54) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| SCHEMBL4607575 | 0.70 | ALDH1A1 (0.45) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| SCHEMBL10726489 | 0.69 | ALDH1A1 (0.55) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| SCHEMBL15095465 | 0.68 | ALDH1A1 (0.58) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| SCHEMBL4272254 | 0.68 | DDB1 (0.51) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| SCHEMBL21160844 | 0.67 | CTRB1 (0.45) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| SCHEMBL16661304 | 0.66 | DDB1 (0.56) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| SCHEMBL20156647 | 0.66 | DDB1 (0.46) | ALDH1A1DDB1CRBNTDP1MAPK1 | |
| Hydrazine SCHEMBL28257347 | 0.66 | ALDH1A1 (0.92) | ALDH1A1TDP1MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL1504008 | 0.65 | DDB1 (0.59) | ALDH1A1DDB1CRBNTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | claimed |
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4851422-A | Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |