Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 9/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966924 | 1.00 | PPARG (0.42) | PPARGMAPTNR2F2HTTSMN1; SMN2 | |
| SCHEMBL967355 | 0.90 | PPARG (0.48) | PPARGMAPTNR2F2HTTSMN1; SMN2 | |
| SCHEMBL967358 | 0.90 | PPARG (0.48) | PPARGMAPTNR2F2HTTSMN1; SMN2 | |
| SCHEMBL964832 | 0.87 | MAPT (0.36) | PPARGMAPTNR2F2HTTSMN1; SMN2 | |
| SCHEMBL964830 | 0.87 | MAPT (0.36) | PPARGMAPTNR2F2HTTSMN1; SMN2 | |
| SCHEMBL5111968 | 0.84 | SMN1; SMN2 (0.41) | MAPTNR2F2HTTSMN1; SMN2PHGDH | |
| SCHEMBL5111983 | 0.84 | SMN1; SMN2 (0.41) | MAPTNR2F2HTTSMN1; SMN2PHGDH | |
| SCHEMBL965976 | 0.84 | MEN1 (0.38) | PPARGMAPTNR2F2HTTSMN1; SMN2 | |
| SCHEMBL965974 | 0.84 | MEN1 (0.38) | PPARGMAPTNR2F2HTTSMN1; SMN2 | |
| SCHEMBL963218 | 0.84 | PPARG (0.48) | PPARGMAPTNR2F2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-13 | — | — | US | disclosed |
| US-20080194617-A1 | Fused ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194617-A1 | Fused ring compound | SLC5A1, SLC5A2, GPR119 | PPARG 248/4885MAPT 4343/4885NR2F2 2010/4885 |
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | PPARA, PPARD, PPARG | PPARG 3/4885MAPT 4720/4885NR2F2 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.