Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669142 | 0.87 | ALDH1A1 (0.38) | KDM4EALDH1A1AOC3HTTMME | |
| SCHEMBL9667737 | 0.85 | CYP2C9 (0.39) | GRM2GRM3AOC3 | |
| SCHEMBL9668337 | 0.84 | ALDH1A1 (0.36) | KDM4EALDH1A1AOC3HTTMME | |
| SCHEMBL9669402 | 0.77 | CYP2D6 (0.38) | KDM4EALDH1A1AOC3HTTDPP4 | |
| SCHEMBL9669450 | 0.73 | ALDH1A1 (0.38) | KDM4EALDH1A1AOC3HTTMME | |
| SCHEMBL20290812 | 0.72 | MEN1 (0.46) | GRM2GRM3ALDH1A1HTT | |
| SCHEMBL9669064 | 0.72 | CYP2C9 (0.40) | AOC3 | |
| SCHEMBL27644091 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1AOC3HTTMME | |
| SCHEMBL9669068 | 0.70 | MEN1 (0.38) | AOC3 | |
| SCHEMBL27665715 | 0.69 | MME (0.41) | KDM4EALDH1A1HTTMMEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293351-B1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |
| US-4990534-A | Aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1991-02-05 | — | — | US | disclosed |