Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668337 | 0.88 | ALDH1A1 (0.36) | ALDH1A1KDM4EAOC3HTTLMNA | |
| SCHEMBL9669476 | 0.87 | GRM2 (0.37) | ALDH1A1KDM4EAOC3HTTMME | |
| SCHEMBL9669064 | 0.85 | CYP2C9 (0.40) | AOC3LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9669450 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EAOC3HTTLMNA | |
| SCHEMBL9669099 | 0.78 | LMNA (0.43) | ALDH1A1HTTLMNACYP2C9CYP2C19 | |
| SCHEMBL9669402 | 0.78 | CYP2D6 (0.38) | ALDH1A1KDM4EAOC3HTTDPP4 | |
| SCHEMBL9667882 | 0.74 | L3MBTL1 (0.38) | ALDH1A1KDM4EHTTLMNANPSR1 | |
| SCHEMBL9669068 | 0.74 | MEN1 (0.38) | AOC3LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9667737 | 0.72 | CYP2C9 (0.39) | AOC3LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9776960 | 0.71 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293351-B1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |
| US-4990534-A | Aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1991-02-05 | — | — | US | disclosed |
| EP-0362264-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988009327-A1 | NEW ARALKYL ESTERS AND PROCESSES FOR THEIR PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1988-12-01 | — | — | WO | disclosed |
| EP-0293351-A2 | New aralkyl esters and processes for their preparation | AKTIEBOLAGET ASTRA (SE) | 1988-11-30 | — | — | EP | disclosed |