Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839168 | 0.83 | CYP1A2 (0.39) | KMT2AMEN1CYP2C9GPR84KDM4E | |
| SCHEMBL6838825 | 0.83 | CYP1A2 (0.39) | MAPTGPR84KDM4E | |
| SCHEMBL1999459 | 0.75 | BCL2 (0.41) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL9129790 | 0.75 | PARP15 (0.41) | MAOAMAOB | |
| SCHEMBL10200201 | 0.75 | ALOX5 (0.53) | KMT2AMEN1MAOAMAOBPTGS1 | |
| SCHEMBL27812638 | 0.73 | CA12 (0.47) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL8896873 | 0.71 | KMT2A (0.35) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL8502109 | 0.71 | PDE4A (0.32) | — | |
| SCHEMBL7239633 | 0.70 | BRD4 (0.39) | KMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL15772419 | 0.69 | CA12 (0.56) | MAPTKMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175464-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4727150-A | ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| EP-0175464-A1 | Benzimidazole derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-03-26 | — | — | EP | disclosed |