Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.66 |
| ▸ | CNR2 | P34972 | 2/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827256 | 0.89 | L3MBTL1 (0.80) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL17324721 | 0.85 | POLB (0.79) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL30049353 | 0.85 | POLB (0.79) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL1606606 | 0.84 | LMNA (0.80) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL5852445 | 0.84 | NPSR1 (0.81) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL16979075 | 0.84 | KMT2A (0.75) | L3MBTL1KMT2AMEN1CNR2CNR1 | |
| SCHEMBL3865315 | 0.83 | L3MBTL1 (0.71) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL27581037 | 0.82 | L3MBTL1 (0.69) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL5625905 | 0.82 | ADORA1 (0.78) | L3MBTL1KMT2AMAPK1NPSR1MEN1 | |
| SCHEMBL20838611 | 0.82 | L3MBTL1 (0.69) | L3MBTL1KMT2AMAPK1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926282-B2 | Phthalazinones and isoquinolinones as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-27 | — | — | US | disclosed |
| CN-103420894-A | 2- butane-1,4-diketone compounds, preparation method and applications | SHANGHAI INST MATERIA MEDICA | 2013-12-04 | — | — | CN | disclosed |
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | disclosed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | disclosed |