Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113974 | 0.79 | ALDH1A1 (0.48) | TSHRGAAALDH1A1HPGDPOLB | |
| SCHEMBL16157907 | 0.71 | KDM4E (0.53) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10436781 | 0.70 | SMN1; SMN2 (0.49) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL8252276 | 0.69 | ALDH1A1 (0.42) | L3MBTL1MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2256676 | 0.66 | SMN1; SMN2 (0.39) | TSHRL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL9645875 | 0.65 | CA1 (0.43) | TSHRL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL30109225 | 0.65 | KMT2A (0.42) | TSHRL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL2117227 | 0.65 | KMT2A (0.42) | TSHRL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL12912993 | 0.64 | NPC1 (0.44) | L3MBTL1MEN1KMT2ATDP1GAA | |
| SCHEMBL10485304 | 0.64 | GAA (0.66) | L3MBTL1MAPTGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |