Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924246 | 0.74 | TSHR (0.46) | RAB9AALDH1A1MAPTGAALMNA | |
| SCHEMBL1613176 | 0.74 | TDP1 (0.43) | CA1CA2ACHEKDM4EALDH1A1 | |
| SCHEMBL5113974 | 0.73 | ALDH1A1 (0.48) | KDM4ERAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7249971 | 0.70 | MAPT (0.49) | KDM4ECACNA1CRAB9AALDH1A1MAPT | |
| SCHEMBL7204453 | 0.69 | ALDH1A1 (0.60) | CA1CA2KDM4EALDH1A1MAPT | |
| SCHEMBL2035595 | 0.69 | ALDH1A1 (0.50) | KDM4ERAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10474720 | 0.67 | ALDH1A1 (0.53) | KDM4ECACNA1CRAB9AALDH1A1MAPT | |
| SCHEMBL6922293 | 0.67 | MAPT (0.46) | KDM4ECACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL2052185 | 0.67 | LMNA (0.43) | KDM4ERAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL259703 | 0.67 | ALDH1A1 (0.50) | RAB9AALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |