Toluene

Toluene

SCHEMBL967006

Cc1ccccc1.[V]C1=CC=CC1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
ACHE P22303 1/20 0.48
HPGD P15428 1/20 0.32
POLB P06746 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL969522 0.89 ACHE (0.40) ACHE
Benzene SCHEMBL968134 0.86
Naphthalene SCHEMBL6811607 0.82 CYP2A6 (0.38) ALOX12
SCHEMBL968041 0.81
Toluene SCHEMBL28651130 0.80 ACHE (0.50) LMNATSHRALOX12ACHEHPGD
Phenol SCHEMBL6812323 0.79 CA12 (0.44)
Hexamethylbenzene SCHEMBL965380 0.79
Anthracene SCHEMBL6813305 0.78 ALDH1A1 (0.37) ACHEHPGD
Hydrochloric Acid SCHEMBL967773 0.78
Hydrochloric Acid SCHEMBL965556 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868103-B2 Method for producing polybutadiene UBE INDUSTRIES, LTD. (JP) 2011-01-11 US disclosed
EP-0919574-B1 Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared UBE INDUSTRIES (JP) 2004-02-11 EP disclosed
US-6300450-B1 Conjugated diene compound polymerization catalyst process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared UBE INDUSTRIES, LTD. (JP) 2001-10-09 US disclosed
EP-0919574-A1 Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared Ube Industries, Ltd. (JP) 1999-06-02 EP disclosed