Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671403 | 0.84 | PDE7A (1.00) | PDE7APTGS2ALDH1A1TSHRPLA2G1B | |
| SCHEMBL9670342 | 0.83 | PDE7A (0.72) | PDE7APTGS2ALDH1A1TSHRPLA2G1B | |
| SCHEMBL9672681 | 0.81 | PDE7A (0.85) | PDE7APTGS2ALDH1A1TSHRPLA2G1B | |
| SCHEMBL9670259 | 0.80 | PDE7A (0.76) | PDE7A | |
| SCHEMBL9672666 | 0.77 | PDE7A (0.77) | PDE7APTGS2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9672832 | 0.77 | PDE7A (0.80) | PDE7APTGS2ALDH1A1TSHRPDE7B | |
| SCHEMBL9823294 | 0.77 | PIK3CD (0.42) | PDE7AALDH1A1GAA | |
| SCHEMBL9671578 | 0.76 | PDE7A (0.76) | PDE7APTGS2 | |
| SCHEMBL9670401 | 0.76 | PDE7A (0.76) | PDE7APTGS2 | |
| SCHEMBL9381672 | 0.76 | PDE7A (0.80) | PDE7APTGS2ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276825-B1 | 4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5008266-A | Antiulcer agent | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4861780-A | 4(3H)-quinazolinone derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0276825-A1 | 4 (3H)-Quinazolinone derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |