Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823553 | 0.88 | PDE7A (0.44) | PDE7AKDM4ELMNAGAAHPGD | |
| SCHEMBL9823497 | 0.88 | TUBB4A (0.45) | PDE7AALDH1A1KDM4ELMNAGAA | |
| SCHEMBL6483730 | 0.87 | PDE7A (0.58) | PDE7AALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9823659 | 0.82 | PDE7A (0.46) | PDE7AALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9823612 | 0.80 | MEN1 (0.53) | PDE7AALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL9823624 | 0.78 | POLB (0.57) | PDE7AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9823808 | 0.78 | ALDH1A1 (0.53) | PDE7AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9823613 | 0.77 | PDE7A (0.44) | PDE7AALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9823294 | 0.77 | PIK3CD (0.42) | PDE7AALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9670401 | 0.77 | PDE7A (0.76) | PDE7APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276826-B1 | 2-ALKYLSULFINYL-4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4833144-A | ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0276826-A1 | 2-Alkylsulfinyl-4 (3H)-quinazolinone derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |