Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593901 | 0.85 | ADRB1 (1.00) | ADRB1KDM4EALDH1A1SMN1; SMN2SLC6A2 | |
| SCHEMBL9596252 | 0.78 | ADRB1 (1.00) | ADRB1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9670493 | 0.70 | ADRB1 (0.56) | ADRB1SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL24918358 | 0.70 | SLC6A4 (0.64) | ADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25154499 | 0.70 | SLC6A4 (0.64) | ADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25154293 | 0.70 | SLC6A4 (0.64) | ADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7149297 | 0.68 | SLC6A2 (0.69) | ADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21360403 | 0.68 | SLC6A4 (0.69) | ADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20141290 | 0.68 | SLC6A4 (0.69) | ADRB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20140560 | 0.68 | SLC6A4 (0.69) | ADRB1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491709-A1 | 2-SUBSTITUTED-1(4)-ARYL PIPERAZINES AND THE PROCESS FOR THEIR PREPARATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| WO-1991004250-A1 | 2-SUBSTITUTED-1(4)-ARYL PIPERAZINES AND THE PROCESS FOR THEIR PREPARATION | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-04-04 | — | — | WO | disclosed |