Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258910 | 0.89 | TDP1 (0.46) | PPARGPPARASLC6A3IGF1RALOX15 | |
| SCHEMBL10712129 | 0.89 | TDP1 (0.50) | SLC6A3IGF1RALOX15 | |
| SCHEMBL11014472 | 0.88 | ESR1 (0.55) | ESR1ALDH1A1LMNAADRA2AADORA3 | |
| SCHEMBL743000 | 0.85 | HRH1 (0.47) | ALDH1A1LMNACYP3A4HIF1AHSD17B10 | |
| SCHEMBL19232391 | 0.84 | RARB (0.45) | ALDH1A1HSD17B10FDFT1 | |
| SCHEMBL19824586 | 0.84 | FDFT1 (0.53) | FDFT1 | |
| SCHEMBL6779846 | 0.84 | TDP1 (0.50) | SLC6A3 | |
| SCHEMBL10571640 | 0.83 | LMNA (0.47) | ESR1ALDH1A1LMNAADRA2AADORA3 | |
| SCHEMBL19226789 | 0.83 | FDFT1 (0.48) | FDFT1IGF1RALOX15 | |
| SCHEMBL17193506 | 0.83 | RARB (0.44) | ALDH1A1HSD17B10FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |