Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10712129 | 0.96 | TDP1 (0.50) | TDP1MAOBHTR2AIGF1RALOX15 | |
| SCHEMBL6779846 | 0.92 | TDP1 (0.50) | TDP1MAOBHTR2AHDAC3MAPK1 | |
| SCHEMBL19824586 | 0.91 | FDFT1 (0.53) | HDAC1HDAC2FFAR1 | |
| SCHEMBL9670504 | 0.89 | CA2 (0.37) | IGF1RALOX15SLC6A3PPARGPPARA | |
| SCHEMBL11693551 | 0.86 | TRPA1 (0.46) | TDP1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL6989076 | 0.85 | ALDH1A1 (0.50) | TDP1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL112814 | 0.83 | SIGMAR1 (0.46) | TDP1ADRA1ASLC6A3GRIK1 | |
| SCHEMBL4595228 | 0.83 | TDP1 (0.54) | TDP1HTR2AALOX15SMN1; SMN2 | |
| SCHEMBL11274710 | 0.83 | TDP1 (0.44) | TDP1IGF1RALOX15SMN1; SMN2 | |
| SCHEMBL5448101 | 0.79 | LTA4H (0.68) | SLC6A3HDAC6FFAR1LTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931838-B1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |