Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670512 | 0.89 | KMT2A (0.56) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9668903 | 0.86 | DPP4 (0.47) | KMT2AEPHA2FLT4GSK3BRARB | |
| Hydrochloric Acid SCHEMBL9670834 | 0.85 | DPP4 (0.46) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9670617 | 0.84 | LMNA (0.51) | KMT2ADPP4LMNAKDM4EALDH1A1 | |
| SCHEMBL9669597 | 0.82 | LMNA (0.50) | KMT2ALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL10649327 | 0.81 | KDM4E (0.39) | KMT2ALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL10757394 | 0.81 | DPP4 (0.48) | KMT2AEPHA2FLT4GSK3BRARB | |
| Hydrochloric Acid SCHEMBL9668992 | 0.80 | KDM4E (0.38) | KMT2ALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL6211209 | 0.77 | LMNA (0.37) | KMT2AEPHA2FLT4GSK3BRARB | |
| SCHEMBL9216042 | 0.76 | EPHA2 (0.45) | KMT2AEPHA2FLT4GSK3BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274033-B1 | PROCESS FOR THE PREPARATION OF QUINOLINECARBOXYLIC ACIDS | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |
| EP-0230274-A2 | Derivatives of 7-(azabicycloalkyl)-quinoloncarboxylic acid and -naphthyridoncarboxylic acid | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |