Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670607 | 0.94 | DPP4 (0.47) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL9670589 | 0.88 | DPP4 (0.59) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL9838674 | 0.86 | LMNA (0.50) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9838693 | 0.84 | DPP4 (0.45) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL10757394 | 0.83 | DPP4 (0.48) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL9839450 | 0.82 | LMNA (0.50) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL10874661 | 0.82 | DPP4 (0.49) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL9748487 | 0.81 | KDM4E (0.48) | KDM4ELMNAHSD17B10 | |
| SCHEMBL9668903 | 0.81 | DPP4 (0.47) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL9670973 | 0.81 | KDM4E (0.48) | KDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | claimed |
| EP-0274033-B1 | PROCESS FOR THE PREPARATION OF QUINOLINECARBOXYLIC ACIDS | BAYER AG (DE) | 1992-03-11 | — | — | EP | disclosed |
| EP-0274033-A1 | Process for the preparation of quinolinecarboxylic acids | BAYER AG (DE) | 1988-07-13 | — | — | EP | disclosed |
| EP-0230274-A2 | Derivatives of 7-(azabicycloalkyl)-quinoloncarboxylic acid and -naphthyridoncarboxylic acid | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |