Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838619 | 0.88 | DPP4 (0.56) | DPP4CHRM2DRD1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9838610 | 0.87 | DPP4 (0.56) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9670593 | 0.84 | DPP4 (0.46) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9669866 | 0.83 | DPP4 (0.55) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10757394 | 0.83 | DPP4 (0.48) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9838657 | 0.83 | LMNA (0.49) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9670607 | 0.83 | DPP4 (0.47) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9216283 | 0.83 | DPP4 (0.51) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9217626 | 0.83 | DPP4 (0.51) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9669912 | 0.82 | KDM4E (0.47) | KDM4ELMNAHSD17B10TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | claimed |