Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668769 | 0.80 | NPC1 (0.55) | ALDH1A1MEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL9669375 | 0.78 | EGLN1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL1590382 | 0.76 | CHEK1 (0.57) | ALDH1A1MEN1PKMKMT2AMAPK1 | |
| SCHEMBL1589931 | 0.76 | GAA (0.56) | ALDH1A1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL9670630 | 0.76 | ROCK2 (0.55) | MEN1PKMKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9671325 | 0.76 | LCK (0.46) | ALDH1A1MEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL13556344 | 0.75 | MAPT (0.43) | ALDH1A1MEN1PKMKMT2ASMN1; SMN2 | |
| SCHEMBL30912936 | 0.72 | EGLN1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL29086882 | 0.72 | EGLN1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL13210698 | 0.72 | KCNMA1 (0.74) | ALDH1A1MEN1PKMKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254322-B1 | BENZIMIDAZOLE DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4886803-A | CARDIOTONIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0254322-A1 | Benzimidazole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |