Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672873 | 0.91 | SLC2A1 (0.57) | THRBTHRASLC2A1ALDH1A1SLC6A4 | |
| SCHEMBL10226109 | 0.88 | ALDH1A1 (0.54) | THRBTHRAALDH1A1SIGMAR1 | |
| SCHEMBL11478126 | 0.82 | SLC2A1 (0.49) | THRBTHRASLC2A1ALDH1A1SLC6A4 | |
| SCHEMBL5092231 | 0.82 | SLC2A1 (0.49) | THRBTHRASLC2A1ALDH1A1SLC6A4 | |
| SCHEMBL11534561 | 0.81 | ALDH1A1 (0.56) | SLC2A1ALDH1A1SIGMAR1KDM4E | |
| SCHEMBL9670815 | 0.79 | SLC2A1 (0.76) | THRBTHRASLC2A1ALDH1A1SIGMAR1 | |
| Methylamine SCHEMBL9871536 | 0.78 | ALDH1A1 (0.52) | SLC2A1ALDH1A1SLC6A4SIGMAR1KDM4E | |
| SCHEMBL6057646 | 0.77 | THRB (0.58) | THRBTHRASLC2A1ALDH1A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL6057774 | 0.76 | THRB (0.57) | THRBTHRASLC2A1ALDH1A1SLC6A4 | |
| SCHEMBL8588324 | 0.76 | SLC6A4 (0.58) | THRBTHRASLC2A1ALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |