Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 13/20 | 0.42 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887825 | 0.91 | EPHX1 (0.47) | EPHX1ACHEPRKCA | |
| SCHEMBL9671386 | 0.89 | EPHX1 (0.43) | EPHX1ACHE | |
| SCHEMBL9670766 | 0.81 | EPHX2 (0.47) | EPHX1 | |
| SCHEMBL10540750 | 0.81 | ZDHHC2 (0.46) | — | |
| SCHEMBL10872983 | 0.79 | ACHE (0.36) | ACHE | |
| SCHEMBL9671112 | 0.79 | EPHX1 (0.34) | EPHX1ACHE | |
| SCHEMBL9672112 | 0.79 | EPHX1 (0.34) | EPHX1ACHE | |
| SCHEMBL8307698 | 0.78 | EPHX1 (0.50) | EPHX1ACHE | |
| SCHEMBL8304388 | 0.78 | EPHX1 (0.50) | EPHX1ACHE | |
| SCHEMBL10907509 | 0.78 | ACHE (0.37) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321296-B1 | LIPID DERIVATIVES THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-5138067-A | PAF antagonists, antithrombotic, antivasoconstricting, antibronchoconstricting or antitumor agents | SHIONOGI & CO. LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5047540-A | Platelet Activating Factor Antagonists and Antitumor Agents | SHIONOGI & CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| US-4868319-A | Process for the preparation of monoalkylcarbamate group-containing compounds | SANDOZ PHARM. CORP. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4820718-A | PLATELET ACTIVATING FACTOR INHIBITORS | SANDOZ PHARM. CORP. (US) | 1989-04-11 | — | — | US | disclosed |