SCHEMBL9670756

SCHEMBL9670756

O=C1CCc2cc(Cl)c(N3C(=O)C4=C(CCCC4)C3=O)cc21

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 1/20 0.34
GRM4 Q14833 1/20 0.34
PBRM1 Q86U86 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9671040 0.82 GRM7 (0.40) GRM7GRM4
SCHEMBL9772336 0.73 GRM7 (0.39) GRM7GRM4
SCHEMBL1512735 0.72 PBRM1 (0.47) PBRM1
SCHEMBL31591225 0.72 PBRM1 (0.47) PBRM1
SCHEMBL9670877 0.72 PBRM1 (0.46) PBRM1
SCHEMBL7160006 0.71 PPOX (0.35) GRM7GRM4
SCHEMBL10765350 0.70 GRM7 (0.39) GRM7GRM4
SCHEMBL10388742 0.69 MAOA (0.50) PBRM1
SCHEMBL9765151 0.69 GRM7 (0.36) GRM7GRM4
SCHEMBL9015717 0.68 PPOX (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0275131-B1 HERBICIDAL OXOINDANES AND TETRAHYDRONAPHTHALENES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-09-23 EP disclosed
EP-0275131-A1 Herbicidal oxoindanes and tetrahydronaphthalenes SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-07-20 EP disclosed