Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672217 | 0.88 | HRH3 (0.59) | PHLPP2GAAALDH1A1MAPTLMNA | |
| SCHEMBL9670566 | 0.84 | THRA (0.53) | PHLPP2GAAALDH1A1MAPTLMNA | |
| SCHEMBL8963488 | 0.82 | PHLPP2 (0.83) | PHLPP2GAAALDH1A1MAPTLMNA | |
| SCHEMBL6057646 | 0.81 | THRB (0.58) | GAAALDH1A1MAPTHRH3RAB9A | |
| Hydrochloric Acid SCHEMBL6057774 | 0.79 | THRB (0.57) | GAAALDH1A1MAPTHRH3RAB9A | |
| Iodomethane SCHEMBL9670336 | 0.79 | PHLPP2 (0.60) | PHLPP2GAAALDH1A1MAPTLMNA | |
| SCHEMBL9629064 | 0.78 | GAA (0.84) | PHLPP2GAAALDH1A1MAPTLMNA | |
| SCHEMBL9672930 | 0.78 | THRB (0.56) | GAAALDH1A1HRH3HTR2AHTR2C | |
| SCHEMBL34468111 | 0.77 | PHLPP2 (0.71) | PHLPP2GAAALDH1A1MAPTLMNA | |
| SCHEMBL9672919 | 0.77 | THRB (0.55) | GAAALDH1A1HRH3RAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |