Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151880 | 0.85 | HDAC4 (0.51) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL13172392 | 0.83 | HDAC4 (0.50) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL7278958 | 0.83 | EPHX1 (0.50) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL1398866 | 0.81 | HDAC4 (0.53) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL11751597 | 0.80 | CES2 (0.68) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL9558442 | 0.79 | CES2 (0.45) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL8498061 | 0.79 | HDAC4 (0.50) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL9298388 | 0.79 | HDAC4 (0.50) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL9298392 | 0.79 | HDAC4 (0.50) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL29531136 | 0.79 | HDAC4 (0.50) | HDAC4HDAC7HDAC5CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440370-A | Inhibitors of viral replication | 鲁汶天主教大学 | 2018-08-24 | — | — | CN | disclosed |
| CN-104024223-B | Inhibitors of viral replication | 鲁汶天主教大学 | 2018-07-24 | — | — | CN | disclosed |
| CN-1166658-C | 4,5 diaryl-3 (2H) -furanone derivatives as cyclooxygenase-2 inhibitors | ��ʽ����̫ƽ�� | 2004-09-15 | — | — | CN | disclosed |
| CN-1348447-A | 4,5 diaryl-3 (2H) -furanone derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2002-05-08 | — | — | CN | disclosed |
| US-5123954-A | Isomerization; pre-and postemergent treatment of rice paddy fields | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0477626-A1 | 3,4-trans-4-ethyl-1-(substituted phenyl)-3-(substituted phenyl)pyrrolidin-2-ones, method for preparing the same, and herbicidal compositions containing the same as herbicidally active ingredients | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-04-01 | — | — | EP | disclosed |