Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29105024 | 0.93 | CA2 (0.61) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL8364788 | 0.91 | CA2 (0.59) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL9670880 | 0.90 | CA2 (0.64) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL7357654 | 0.89 | CA2 (0.62) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL9810746 | 0.89 | CA2 (0.62) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL26116458 | 0.89 | HDAC3 (0.58) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL8955502 | 0.89 | HDAC3 (0.58) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL26121323 | 0.89 | CA2 (0.57) | CA2KDM4EALDH1A1MAPK1 | |
| SCHEMBL23014948 | 0.89 | ALDH1A1 (0.58) | CA2KDM4EHDAC1HDAC2HDAC3 | |
| SCHEMBL97656 | 0.89 | ALDH1A1 (0.58) | CA2KDM4EHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |