Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752172 | 0.97 | TTR (0.50) | PARP10TTRPOLBSRD5A2AKR1C3 | |
| SCHEMBL9673278 | 0.91 | TTR (0.42) | PARP10TTRPOLBMBTD1L3MBTL3 | |
| SCHEMBL9243809 | 0.89 | POLB (0.47) | PARP10TTRPOLBSRD5A2AKR1C3 | |
| SCHEMBL11332512 | 0.86 | PARP10 (0.46) | PARP10TTRPOLBL3MBTL1 | |
| SCHEMBL9672200 | 0.84 | KMT2A (0.40) | TTRPOLBSRD5A2L3MBTL1 | |
| SCHEMBL9243804 | 0.82 | CTNNB1 (0.62) | PARP10SRD5A2L3MBTL1CTNNB1 | |
| SCHEMBL9249310 | 0.81 | PARP10 (0.64) | PARP10SRD5A2AKR1C3ERCC5FEN1 | |
| SCHEMBL21786 | 0.81 | PARP10 (0.64) | PARP10SRD5A2AKR1C3ERCC5FEN1 | |
| SCHEMBL9243798 | 0.80 | PARP10 (0.53) | PARP10TTRSRD5A2L3MBTL1ERCC5 | |
| Hydrochloric Acid SCHEMBL9672161 | 0.79 | TTR (0.60) | PARP10TTRPOLBSRD5A2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134219-A | STIFF-CHAIN POLYHETEROCYCLES HAVING IMPROVED SOLUBILITY, A PROCESS FOR THEIR PRODUCTION AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-07-28 | — | — | US | disclosed |
| EP-0432562-A1 | Polyhétérocycles with rigid chain and better solubility, their process of production and use | BAYER AG (DE) | 1991-06-19 | — | — | EP | disclosed |