Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PLEC | Q15149 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672152 | 0.91 | PARP10 (0.49) | TTRPOLBMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL8752172 | 0.91 | TTR (0.50) | TTRPOLBBCL2L1MBTD1L3MBTL3 | |
| SCHEMBL11332512 | 0.83 | PARP10 (0.46) | TTRPOLBTDP1L3MBTL1PARP10 | |
| SCHEMBL9325745 | 0.83 | CTNNB1 (0.54) | TDP1MAP3K8CYP1A2GAACYP2C9 | |
| SCHEMBL9671798 | 0.82 | PPARA (0.45) | TTRMCL1BCL2L1 | |
| SCHEMBL9672200 | 0.82 | KMT2A (0.40) | TTRPOLBMCL1L3MBTL1MAPT | |
| SCHEMBL9536693 | 0.81 | PARP10 (0.53) | MCL1BCL2L1PARP10MAPTSMN1; SMN2 | |
| SCHEMBL9243809 | 0.80 | POLB (0.47) | TTRPOLBPARP10SMN1; SMN2 | |
| SCHEMBL9186446 | 0.77 | PARP10 (0.58) | MCL1BCL2L1PARP10SMN1; SMN2 | |
| SCHEMBL9243798 | 0.74 | PARP10 (0.53) | TTRL3MBTL1PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134219-A | STIFF-CHAIN POLYHETEROCYCLES HAVING IMPROVED SOLUBILITY, A PROCESS FOR THEIR PRODUCTION AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 1992-07-28 | — | — | US | disclosed |
| EP-0432562-A1 | Polyhétérocycles with rigid chain and better solubility, their process of production and use | BAYER AG (DE) | 1991-06-19 | — | — | EP | disclosed |