Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672917 | 1.00 | ESR2 (0.43) | ESR2FFAR1AKR1B1TSHRPPARG | |
| SCHEMBL27812997 | 0.76 | ACHE (0.44) | ESR2FFAR1AKR1B1TSHRPPARG | |
| SCHEMBL2692039 | 0.74 | PPARG (0.53) | ESR2FFAR1AKR1B1TSHRPPARG | |
| SCHEMBL633444 | 0.73 | MME (0.48) | ESR2FFAR1AKR1B1TSHRPPARG | |
| SCHEMBL9423804 | 0.73 | ESR2 (0.49) | ESR2FFAR1AKR1B1PPARGMME | |
| Hydrochloric Acid SCHEMBL9844253 | 0.73 | LTB4R2 (0.47) | ESR2FFAR1AKR1B1TSHRPPARG | |
| SCHEMBL4253889 | 0.73 | HSD17B10 (0.58) | ESR2FFAR1AKR1B1TSHRPPARG | |
| SCHEMBL6953214 | 0.72 | ESR2 (0.59) | ESR2FFAR1AKR1B1PPARGMME | |
| SCHEMBL1900 | 0.72 | LTB4R2 (0.53) | FFAR1AKR1B1TSHRLTB4R2AGTR1 | |
| SCHEMBL10718048 | 0.72 | HSD17B10 (0.60) | ESR2FFAR1AKR1B1TSHRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475898-A1 | Azacyclic compounds | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |