Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327905 | 0.80 | DRD2 (0.46) | MAPTL3MBTL1 | |
| SCHEMBL9672908 | 0.78 | HTR2C (0.48) | CA1CA2CA4CA7GAA | |
| SCHEMBL13926363 | 0.78 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL15328003 | 0.78 | DRD2 (0.46) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15328043 | 0.78 | DRD2 (0.46) | F2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15328097 | 0.77 | HTR2A (0.54) | PRMT1MAPT | |
| SCHEMBL5585348 | 0.77 | MEN1 (0.62) | F10F2PRSS1PRMT1MEN1 | |
| SCHEMBL17993502 | 0.76 | DRD2 (0.50) | F10F2PRSS1PRMT1MEN1 | |
| SCHEMBL9674301 | 0.75 | CA12 (0.42) | CA12CA1CA2CA4CA6 | |
| SCHEMBL15328020 | 0.74 | HDAC1 (0.48) | F10MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251143-B1 | 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines | Bristol-Myers Squibb GmbH (DE) | 1992-08-26 | — | — | EP | disclosed |
| US-4801705-A | 2-oxo-1-(((substituted sulfonyl)amino)-carbonyl)azetidines | E. R. SQUIBB & SONS, INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0251143-A1 | 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines | Bristol-Myers Squibb GmbH (DE) | 1988-01-07 | — | — | EP | disclosed |