Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12514597 | 0.90 | ALDH1A1 (0.61) | FFAR1LTA4HALDH1A1HPGDALOX15 | |
| SCHEMBL2201304 | 0.87 | FFAR1 (0.62) | FFAR1LTA4HTSHRPLAAT3PLAAT5 | |
| SCHEMBL19322272 | 0.87 | FFAR1 (0.62) | FFAR1LTA4HTSHRPLAAT3PLAAT5 | |
| SCHEMBL19322285 | 0.85 | FFAR1 (0.60) | FFAR1LTA4HTSHRPLAAT3PLAAT5 | |
| SCHEMBL19322269 | 0.85 | FFAR1 (0.60) | FFAR1LTA4HTSHRPLAAT3PLAAT5 | |
| SCHEMBL19322273 | 0.85 | FFAR1 (0.60) | FFAR1LTA4HTSHRPLAAT3PLAAT5 | |
| SCHEMBL8420664 | 0.85 | KCNA3 (0.59) | FFAR1LTA4HPPARGEPHX2 | |
| SCHEMBL12040543 | 0.83 | FFAR1 (0.58) | FFAR1LTA4HALOX15TSHRPLAAT3 | |
| SCHEMBL416807 | 0.83 | FDFT1 (0.51) | FFAR1FDFT1 | |
| SCHEMBL19322270 | 0.83 | LTA4H (0.67) | FFAR1LTA4HTSHRPLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485026-A2 | Antimanic phenoxymethylene bisphosphonate derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-05-13 | — | — | EP | disclosed |