Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757136 | 0.79 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9636819 | 0.74 | ALOX5AP (0.42) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9635499 | 0.73 | CYSLTR1 (0.40) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9635532 | 0.71 | CYSLTR1 (0.40) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9637032 | 0.70 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9757127 | 0.69 | CYSLTR1 (0.46) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL9635637 | 0.66 | CYSLTR1 (0.37) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9757215 | 0.66 | ALOX5AP (0.38) | CYSLTR1CYSLTR2ALOX5APGPBAR1 | |
| SCHEMBL14021499 | 0.65 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2ALOX5APGPBAR1 | |
| SCHEMBL10544504 | 0.64 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2ALOX5APGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434827-A4 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1992-01-08 | — | — | EP | disclosed |