Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757136 | 0.86 | CYSLTR1 (0.45) | ALOX5APCYSLTR1CYSLTR2 | |
| SCHEMBL9757216 | 0.82 | CYSLTR1 (0.38) | CYSLTR1CYSLTR2 | |
| SCHEMBL9760905 | 0.77 | CYSLTR1 (0.44) | ALOX5APCYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9756990 | 0.75 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757016 | 0.75 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9757125 | 0.74 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9757114 | 0.72 | CYSLTR2 (0.46) | CYSLTR1CYSLTR2 | |
| SCHEMBL9757219 | 0.72 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9757264 | 0.72 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9757105 | 0.71 | GPBAR1 (0.45) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |