Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005110 | 0.81 | TSHR (0.36) | NPC1RAB9AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL7005108 | 0.81 | TSHR (0.36) | NPC1RAB9AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9125199 | 0.77 | RAB9A (0.54) | NPC1RAB9AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9125192 | 0.77 | RAB9A (0.54) | NPC1RAB9AMAPK1TSHRSMN1; SMN2 | |
| Fumaric Acid SCHEMBL9737068 | 0.72 | HSP90AA1 (0.39) | NPC1RAB9ATSHRSMN1; SMN2MEN1 | |
| Fumaric Acid SCHEMBL9737079 | 0.72 | HSP90AA1 (0.39) | NPC1RAB9ATSHRSMN1; SMN2MEN1 | |
| SCHEMBL27417397 | 0.72 | HPGD (0.43) | MAPK1TSHRSMN1; SMN2HPGDMEN1 | |
| SCHEMBL9672584 | 0.72 | NPC1 (0.37) | NPC1RAB9ATSHRSMN1; SMN2HPGD | |
| SCHEMBL9672954 | 0.70 | MEN1 (0.38) | NPC1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL7003258 | 0.70 | NPC1 (0.45) | NPC1RAB9AMAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517877-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992012137-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1992-07-23 | — | — | WO | disclosed |