Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125199 | 0.82 | RAB9A (0.54) | HPGDTSHRALDH1A1ALDH2MAPT | |
| SCHEMBL9125192 | 0.82 | RAB9A (0.54) | HPGDTSHRALDH1A1ALDH2MAPT | |
| SCHEMBL27476781 | 0.78 | ALDH1A1 (0.43) | HPGDTSHRALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL27476782 | 0.78 | ALDH1A1 (0.43) | HPGDTSHRALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL9736298 | 0.74 | ALDH1A1 (0.48) | HPGDTSHRALDH1A1ALDH3A1RCE1 | |
| SCHEMBL9736302 | 0.74 | ALDH1A1 (0.48) | HPGDTSHRALDH1A1ALDH3A1RCE1 | |
| SCHEMBL9674236 | 0.72 | NPC1 (0.35) | HPGDTSHRALDH1A1ALDH2MAPT | |
| SCHEMBL9737468 | 0.69 | HTT (0.62) | HPGDALDH1A1MAPTGAAHTT | |
| SCHEMBL9736840 | 0.69 | HTT (0.47) | HPGDALDH1A1MAPTGAAHTT | |
| SCHEMBL9673291 | 0.69 | HTT (0.62) | HPGDALDH1A1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1088578-A | 3 (2H)-pyridazinone derivatives and preparation method thereof | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1994-06-29 | — | — | CN | disclosed |