Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674284 | 1.00 | CHRNB2 (0.35) | CHRNB2CHRNA4MAPTTDP1L3MBTL1 | |
| SCHEMBL8181814 | 0.91 | CHRNB2 (0.38) | CHRNB2CHRNA4MAPTLMNAKMT2A | |
| SCHEMBL8181812 | 0.91 | CHRNB2 (0.38) | CHRNB2CHRNA4MAPTLMNAKMT2A | |
| SCHEMBL8867255 | 0.90 | MAPT (0.36) | MAPTTDP1L3MBTL1LMNAKMT2A | |
| SCHEMBL8867247 | 0.90 | MAPT (0.36) | MAPTTDP1L3MBTL1LMNAKMT2A | |
| SCHEMBL8866534 | 0.78 | CHRNB2 (0.39) | CHRNB2CHRNA4MAPTKMT2AALDH1A1 | |
| SCHEMBL8866545 | 0.78 | CHRNB2 (0.39) | CHRNB2CHRNA4MAPTKMT2AALDH1A1 | |
| SCHEMBL8867133 | 0.77 | MAPT (0.37) | MAPTL3MBTL1LMNAKMT2ARECQL | |
| SCHEMBL8867137 | 0.77 | MAPT (0.37) | MAPTL3MBTL1LMNAKMT2ARECQL | |
| SCHEMBL7639498 | 0.76 | CHRNB2 (0.39) | CHRNB2CHRNA4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |