Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866534 | 1.00 | CHRNB2 (0.39) | CHRNB2CHRNA4ALDH1A1DGAT1MEN1 | |
| SCHEMBL2755020 | 0.86 | ALDH1A1 (0.43) | CHRNB2CHRNA4ALDH1A1MEN1KMT2A | |
| SCHEMBL8926511 | 0.86 | ALDH1A1 (0.43) | CHRNB2CHRNA4ALDH1A1MEN1KMT2A | |
| SCHEMBL8181812 | 0.86 | CHRNB2 (0.38) | CHRNB2CHRNA4ALDH1A1DGAT1MEN1 | |
| SCHEMBL8181814 | 0.86 | CHRNB2 (0.38) | CHRNB2CHRNA4ALDH1A1DGAT1MEN1 | |
| SCHEMBL8194979 | 0.85 | ALDH1A1 (0.40) | CHRNB2CHRNA4ALDH1A1DGAT1MEN1 | |
| SCHEMBL8194977 | 0.85 | ALDH1A1 (0.40) | CHRNB2CHRNA4ALDH1A1DGAT1MEN1 | |
| SCHEMBL7638475 | 0.82 | CHRNB2 (0.43) | CHRNB2CHRNA4ALDH1A1MEN1KMT2A | |
| SCHEMBL7643543 | 0.82 | CHRNB2 (0.40) | CHRNB2CHRNA4ALDH1A1MEN1KMT2A | |
| SCHEMBL7643537 | 0.82 | CHRNB2 (0.40) | CHRNB2CHRNA4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060615-C | Guanidine derivatives, their production and insecticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-01-17 | — | — | CN | disclosed |
| US-5633375-A | NONTOXIC TO HUMNAS, ANIMALS, FISH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5489603-A | CONTAINING NITROGEN HETEROCYCLIC RINGS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0493369-B1 | Guanidine derivatives, their production and insecticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0665222-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |
| CN-1026981-C | Process for the preparation of guanidine derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-14 | — | — | CN | disclosed |
| CN-1077843-A | GUANIDINE DERIVATIVES, THEIR PRODUCTION AND INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-11-03 | — | — | CN | disclosed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-5034404-A | Nitroguanidines as insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| CN-1045261-A | Guanidine derivatives, their production and pesticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-09-12 | — | — | CN | disclosed |
| EP-0376279-A2 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |