Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592076 | 0.94 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL9590628 | 0.92 | HRH3 (0.56) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL8956385 | 0.92 | HRH3 (0.56) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL9590081 | 0.92 | HRH3 (0.56) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL9593778 | 0.92 | HRH3 (0.56) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL270793 | 0.90 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL17912 | 0.88 | KDM4E (0.56) | SMN1; SMN2CYP3A4KDM4EPOLBKMT2A | |
| SCHEMBL26120882 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL20234326 | 0.87 | HRH3 (0.61) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB | |
| SCHEMBL22248702 | 0.87 | HRH3 (0.62) | SMN1; SMN2CYP3A4HRH3KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259137-B1 | METHOD FOR PRODUCING A OF LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORP (JP) | 2016-08-31 | — | — | EP | disclosed |
| EP-2915796-A1 | PROPYL-PHENYL-ETHER DERIVATIVE AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT, AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | Seiwa Kasei Company, Limited (JP) | 2015-09-09 | — | — | EP | disclosed |
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | SEIWA KASEI COMPANY, LIMITED (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | SEIWA KASEI COMPANY, LIMITED (JP) | 2015-08-27 | — | — | US | disclosed |
| WO-2014069555-A1 | PROPYL-PHENYL-ETHER DERIVATIVE AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT, AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | 株式会社成和化成 (JP) | 2014-05-08 | — | — | WO | disclosed |
| US-20110168044-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2330464-A1 | PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE | FUJIFILM Corporation (JP) | 2011-06-08 | — | — | EP | disclosed |
| US-20110020751-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR | FUJIFILM CORPORATION (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2259137-A1 | ORIGINAL PLATE FOR LITHOGRAPHIC PRINTING PLATE, AND METHOD FOR PRODUCTION OF LITHOGRAPHIC PRINTING PLATE USING THE SAME | FUJIFILM Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-7741289-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2010-06-22 | — | — | US | disclosed |
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-7235543-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2007-06-26 | — | — | US | disclosed |
| US-7196082-B2 | Ophthalmic compositions for treating ocular hypertension | MERCK & CO. INC. (US) | 2007-03-27 | — | — | US | disclosed |
| US-5242936-A | Phenoxy alkanol esters for treatment of allergic conditions | Berger, Frank M. (US) | 1993-09-07 | — | — | US | disclosed |
| US-5021460-A | P-alkyl phenoxy alkanols for the treatment of allergic conditions | Berger, Frank M. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4816491-A | Treatment of allergic conditions using indanyloxy-alkanol derivatives | Berger, Frank M. (US) | 1989-03-28 | — | — | US | disclosed |
| EP-0162975-B1 | P-ALKYL OR CYCLOALKYL PHENOXY ALKANOLS AND ALKANOL ESTERS AND USE FOR THE TREATMENT OF ALLERGIC CONDITIONS | PHARMACO DEVELOPMENT PARTNERS (US) | 1988-07-27 | — | — | EP | disclosed |
| EP-0162975-A1 | P-alkyl or cycloalkyl phenoxy alkanols and alkanol esters and use for the treatment of allergic conditions | PHARMACO DEVELOPMENT PARTNERS (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4543362-A | P-Alkyl or cycloalkyl phenoxy alkanols and alkanol esters and process for the treatment of allergic conditions | Berger, Frank M. (US) | 1985-09-24 | — | — | US | disclosed |
| US-4451474-A | T-Butyl-phenoxy-alkylene esters of benzoic and nicotinic acids, compositions containing same and their antihistaminic method of use | Berger, Frank M. (US) | 1984-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | TYR, MITF, MC1R | SMN1; SMN2 4407/4885CYP3A4 815/4885HRH3 3426/4885 |
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | APOB, NPC1L1, CYP46A1 | SMN1; SMN2 207/4885CYP3A4 594/4885HRH3 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.