Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 3/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673063 | 0.93 | HTR7 (0.39) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9674394 | 0.91 | HPGD (0.37) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9675220 | 0.91 | KDM4E (0.44) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9674743 | 0.89 | PIM1 (0.48) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9672728 | 0.88 | PIM1 (0.36) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9791230 | 0.87 | KDM4E (0.40) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9674400 | 0.86 | PIM1 (0.42) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9522727 | 0.85 | KDM4E (0.47) | PIM1GSK3AGSK3BPIM3HPGD | |
| SCHEMBL9791224 | 0.85 | PIM1 (0.47) | PIM1GSK3AGSK3BPIM3CSNK1G1 | |
| SCHEMBL9234131 | 0.85 | PIM1 (0.39) | PIM1GSK3AGSK3BPIM3CSNK1G1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011831-A | Bactericides | NIPPON SHINYAKU CO. LTD. (JP) | 1991-04-30 | — | — | US | claimed |
| EP-0315827-B1 | DERIVATIVES OF QUINOLINECARBOXYLIC ACID | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5011831-A | Bactericides | NIPPON SHINYAKU CO. LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0315827-A1 | Derivatives of quinolinecarboxylic acid | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | disclosed |