Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673660 | 0.93 | KDM4E (0.42) | KDM4EMEN1KMT2AADRA2BMAPK1 | |
| SCHEMBL9791232 | 0.91 | KMT2A (0.45) | KDM4EMEN1KMT2AADRA2BMAPK1 | |
| SCHEMBL9674476 | 0.91 | PIM1 (0.39) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL9674781 | 0.89 | PIM1 (0.49) | KDM4EMEN1KMT2AADRA2BMAPK1 | |
| SCHEMBL9674329 | 0.88 | KDM4E (0.41) | KDM4EMEN1KMT2AADRA2BMAPK1 | |
| SCHEMBL9673019 | 0.86 | KDM4E (0.46) | KDM4EMEN1KMT2AADRA2BMAPK1 | |
| SCHEMBL9791230 | 0.86 | KDM4E (0.40) | KDM4EMEN1KMT2AADRA2BMAPK1 | |
| SCHEMBL9523011 | 0.85 | LMNA (0.46) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL9229244 | 0.84 | KDM4E (0.46) | KDM4EMEN1KMT2AADRA2BMAPK1 | |
| SCHEMBL9673063 | 0.84 | HTR7 (0.39) | KDM4EMEN1KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011831-A | Bactericides | NIPPON SHINYAKU CO. LTD. (JP) | 1991-04-30 | — | — | US | claimed |
| EP-0315827-B1 | DERIVATIVES OF QUINOLINECARBOXYLIC ACID | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5011831-A | Bactericides | NIPPON SHINYAKU CO. LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0315827-A1 | Derivatives of quinolinecarboxylic acid | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | disclosed |