Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672859 | 0.88 | SMN1; SMN2 (0.40) | POLBSMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9673192 | 0.78 | POLB (0.60) | POLBSMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9673200 | 0.78 | POLB (0.60) | POLBSMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10564195 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9674027 | 0.75 | NR1I3 (0.41) | SMN1; SMN2CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL9673356 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2LTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13243036 | 0.74 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10434807 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2LTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9672273 | 0.73 | L3MBTL1 (0.45) | SMN1; SMN2L3MBTL1PPARGALDH1A1MAPT | |
| SCHEMBL9261813 | 0.72 | LMNA (0.39) | SMN1; SMN2CYP1A2CYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234045-B1 | A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4843068-A | INSECTICIDES, MITICIDES, FUNGICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0234045-A2 | A pyrazole oxime derivative and its production and use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |