Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483043 | 0.81 | PARP1 (0.69) | PARP1HTR3AKCNH2GRM2MAPT | |
| SCHEMBL6139222 | 0.78 | PARP1 (0.44) | PARP1HTR3AKCNH2GRM2MAPT | |
| Ethylene SCHEMBL6511634 | 0.75 | PARP1 (0.42) | PARP1HTR3AKCNH2GRM2MAPT | |
| SCHEMBL6199833 | 0.74 | PARP1 (0.66) | PARP1HTR3AKCNH2GRM2 | |
| SCHEMBL7257414 | 0.73 | KCNH2 (0.39) | PARP1HTR3AKCNH2GRM2 | |
| SCHEMBL7265551 | 0.72 | ATM (0.45) | PARP1HTR3AKCNH2GRM2 | |
| SCHEMBL7257136 | 0.72 | OPRM1 (0.37) | PARP1HTR3AKCNH2GRM2 | |
| SCHEMBL6630805 | 0.71 | PARP1 (0.43) | PARP1HTR3A | |
| SCHEMBL8824023 | 0.71 | PARP1 (0.68) | PARP1HTR3AKCNH2GRM2 | |
| SCHEMBL7257413 | 0.71 | PARP1 (0.36) | PARP1HTR3AKCNH2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |