Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675367 | 0.84 | PPARD (0.37) | PPARDTSHRTDP1MAPTMAPK1 | |
| SCHEMBL10448349 | 0.81 | TSHR (0.56) | PPARDTSHRTP53TDP1 | |
| SCHEMBL31682539 | 0.73 | PPARD (0.44) | PPARDTSHRTP53TDP1 | |
| SCHEMBL9674749 | 0.69 | PPARD (0.54) | PPARDTSHRTP53TDP1 | |
| SCHEMBL161140 | 0.69 | TSHR (0.55) | PPARDTSHRTP53TDP1 | |
| SCHEMBL31682591 | 0.68 | PPARD (0.39) | PPARDTSHR | |
| SCHEMBL15011848 | 0.68 | PPARD (0.52) | PPARDTSHRTP53TDP1MAPT | |
| SCHEMBL18979175 | 0.68 | PPARD (0.52) | PPARDTSHRTP53TDP1MAPT | |
| SCHEMBL246097 | 0.68 | PPARD (0.64) | PPARDTSHRTP53TDP1 | |
| SCHEMBL3889468 | 0.67 | TSHR (0.52) | PPARDTSHRTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | claimed |
| US-5108994-A | Synergistic with interferon; herpes virus | BEECHAM GROUP P.L.C. (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0399743-A1 | Phosphonomethylthio-alkoseypureine derivatives, intermediate products for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-11-28 | — | — | EP | disclosed |