Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448332 | 0.85 | TSHR (0.43) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9675540 | 0.84 | PPARD (0.47) | PPARDTSHRMAPTMAPK1TDP1 | |
| SCHEMBL9685475 | 0.74 | PPARD (0.46) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL8839568 | 0.68 | PPARD (0.46) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL23607016 | 0.68 | TDP1 (0.38) | ALDH1A1LMNAHSD17B10TSHRMAPT | |
| SCHEMBL10448349 | 0.67 | TSHR (0.56) | PPARDTSHRTDP1 | |
| SCHEMBL8764430 | 0.67 | ALDH1A1 (0.50) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9675130 | 0.67 | ALDH1A1 (0.31) | ALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL7972024 | 0.65 | TSHR (0.46) | PPARDTSHRMAPTMAPK1TDP1 | |
| SCHEMBL751991 | 0.64 | PPARD (0.54) | PPARDALDH1A1LMNAHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108994-A | Synergistic with interferon; herpes virus | BEECHAM GROUP P.L.C. (GB) | 1992-04-28 | — | — | US | disclosed |