SCHEMBL161140

SCHEMBL161140

CCOP(=O)(CSC)OCC

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
PPARD Q03181 2/20 0.46
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
KCNH2 Q12809 1/20 0.33
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3889468 0.77 TSHR (0.52) TSHRPPARDTP53TDP1MEN1
SCHEMBL15307443 0.77
SCHEMBL11696718 0.77 PPARD (0.50) TSHRPPARDTP53TDP1
SCHEMBL7891394 0.75
SCHEMBL4971866 0.75 TSHR (0.71) TSHRPPARDTP53TDP1MEN1
SCHEMBL13529619 0.73 TSHR (0.48) TSHRPPARDTP53TDP1MEN1
SCHEMBL3485999 0.72 TSHR (0.60) TSHRPPARDTP53TDP1MEN1
SCHEMBL282085 0.72 TSHR (0.60) TSHRPPARDTP53TDP1MEN1
SCHEMBL29099484 0.72 TSHR (0.65) TSHRPPARDTP53TDP1MEN1
SCHEMBL7972024 0.72 TSHR (0.46) TSHRPPARDTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400793-A1 COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2024-12-05 US claimed
CN-118434796-A Composition for polyurethane foam, foam prepared therefrom and method thereof 迈图高新材料公司 2024-08-02 CN claimed
EP-4396271-A1 COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF Momentive Performance Materials Inc. (US) 2024-07-10 EP claimed
CN-116987116-B Continuous synthesis method of diethyl methylthiomethyl phosphate 常州合全药业有限公司 2023-12-01 CN claimed
CN-116987116-A Continuous synthesis method of diethyl methylthiomethyl phosphate 常州合全药业有限公司 2023-11-03 CN claimed
WO-2023034354-A1 COMPOSITION FOR POLYURETHANE FOAM, FOAM PREPARED THEREFROM AND A METHOD THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2023-03-09 WO claimed
US-8062816-B2 Phosphonate hole blocking layer photoconductors XEROX CORPORATION (US) 2011-11-22 US claimed
US-8053151-B2 Phosphonate containing photoconductors XEROX CORPORATION (US) 2011-11-08 US claimed
US-20090325091-A1 PHOSPHONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-20090297967-A1 PHOSPHONATE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-03 US claimed
EP-2128709-A1 Phosphonate Hole Blocking Layer Photoconductors Xerox Corporation (US) 2009-12-02 EP claimed
US-20260135164-A1 LITHIUM SECONDARY BATTERIES CAPABLE OF SELF-POISONING PROLOGIUM TECHNOLOGY CO., LTD. (TW) 2026-05-14 US disclosed
EP-4668366-A1 LITHIUM SECONDARY BATTERY CAPABLE OF SELF-POISONING Prologium Technology Co., Ltd. (TW) 2025-12-24 EP disclosed
WO-2025073792-A1 WRN INHIBITORY COMPOUNDS FORX THERAPEUTICS AG (CH) 2025-04-10 WO disclosed
US-20250026721-A1 COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K VIVIDION THERAPEUTICS, INC. 2025-01-23 US disclosed
EP-0756625-A1 IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS ARRIS PHARMACEUTICAL CORPORATION (US) 1997-02-05 EP disclosed
WO-1995023222-A1 IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS KHEPRI PHARMACEUTICALS, INC. (US) 1995-08-31 WO disclosed
US-4388237-A NEUROLEPTIC, SEDATIVE, HYPNOTIC, ANALGESIC, ANTIDEPRESSANT BASF AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0063489-A1 4\"-Modified methylene oleandomycins PFIZER INC. (US) 1982-10-27 EP disclosed
US-4336368-A 4 Deoxy-4-methylene oleandomycin and derivatives thereof PFIZER INC. (US) 1982-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260135164-A1 LITHIUM SECONDARY BATTERIES CAPABLE OF SELF-POISONING L3MBTL3, HAO2, LDHB TSHR 3143/4885PPARD 4441/4885TP53 553/4885
US-20250026721-A1 COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K KRAS, HRAS, NRAS TSHR 2577/4885PPARD 2857/4885TP53 149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.