Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575902 | 0.82 | PDK2 (0.45) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL360806 | 0.79 | ALDH1A1 (0.48) | PDK1PDK2PDK3PDK4CA2 | |
| SCHEMBL29845612 | 0.79 | CYP1A2 (0.39) | PDK1PDK2PDK3PDK4CA12 | |
| SCHEMBL9677685 | 0.79 | GAA (0.38) | ALDH1A1ALOX15CYP2C9SMN1; SMN2LMNA | |
| SCHEMBL5071051 | 0.78 | CYP2C9 (0.52) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL17674663 | 0.77 | PDK2 (0.45) | PDK1PDK2PDK3PDK4CA12 | |
| SCHEMBL16815415 | 0.76 | ALDH1A1 (0.56) | CA12CA1CA2CA4CA7 | |
| SCHEMBL1826833 | 0.76 | GABRA1 (0.41) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL15834065 | 0.76 | PDK2 (0.40) | PDK1PDK2PDK3PDK4CA12 | |
| SCHEMBL891405 | 0.76 | ALDH1A1 (0.56) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4880781-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1989-11-14 | — | — | US | disclosed |