Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361309 | 1.00 | USP2 (0.40) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4361313 | 1.00 | USP2 (0.40) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4465846 | 0.89 | USP2 (0.48) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4465842 | 0.89 | USP2 (0.48) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL6118063 | 0.89 | USP2 (0.48) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL17952574 | 0.88 | PTGS1 (0.50) | TSHRKDM4EALDH1A1LMNAALOX15 | |
| SCHEMBL7804173 | 0.81 | ALDH1A1 (0.37) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL777710 | 0.78 | PTGS1 (0.36) | ALDH1A1PTGS1 | |
| SCHEMBL7480573 | 0.77 | — | — | |
| SCHEMBL7480571 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232912-B1 | HYDROXAMIC ACIDS OF 7-OXABICYCLOHEPTANE SUBSTITUTED ETHERS | E.R. Squibb & Sons, Inc. (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0232912-A1 | Hydroxamic acids of 7-oxabicycloheptane substituted ethers | E.R. Squibb & Sons, Inc. (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4654366-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPSORIATIC | E. R. SQUIBB & SONS, INC. (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0163562-A1 | 7-Oxabicycloheptane substituted ethers | E.R. Squibb & Sons, Inc. (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4550120-A | BRONCHODILATOR AGENTS, ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1985-10-29 | — | — | US | disclosed |