Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 4/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676526 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL22296756 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL22900003 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL7542669 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL7539826 | 0.80 | POLB (0.59) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL26724937 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL19432460 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL9675542 | 0.80 | POLB (0.59) | SMN1; SMN2RAB9APREPDPP4DPP8 | |
| SCHEMBL14558048 | 0.76 | ITGB1 (0.41) | RAB9AHCRTR2 | |
| SCHEMBL12413729 | 0.76 | HRH3 (0.49) | CYP2D6PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4880781-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |