Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.41 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296756 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2D6DPP4DPP8DPP9 | |
| SCHEMBL22900003 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP2D6DPP4DPP8DPP9 | |
| SCHEMBL26997900 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2HCRTR2XPNPEP1CYP2D6DPP4 | |
| SCHEMBL9676526 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2HCRTR2CYP2D6DPP4DPP8 | |
| SCHEMBL9675632 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2HCRTR2CYP2D6DPP4DPP8 | |
| SCHEMBL3973116 | 0.81 | RAB9A (0.57) | HCRTR2XPNPEP1RAB9A | |
| SCHEMBL2546757 | 0.80 | POLB (0.41) | HCRTR2XPNPEP1DPP4POLBL3MBTL1 | |
| SCHEMBL793131 | 0.80 | POLB (0.41) | HCRTR2XPNPEP1DPP4POLBL3MBTL1 | |
| SCHEMBL2788731 | 0.80 | POLB (0.41) | HCRTR2XPNPEP1DPP4POLBL3MBTL1 | |
| SCHEMBL7541055 | 0.79 | HCRTR2 (0.39) | HCRTR2DPP4DPP7POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |